Blar i forfatter "Mochol, Monika"

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    • Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation 

      Mochol, Monika; Taubøll, Erik; Aukrust, Pål; Ueland, Thor; Andreassen, Ole Andreas; Svalheim, Sigrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-29)
      <i>Purpose</i> - Proinflammatory cytokines seems to play a role in epileptogenesis independent of the underlying cause. The purpose of this study was to assess if IL-18 and its binding protein IL-18BP are related to epilepsy and could act as a predictive biomarker for epileptogenesis.<p> <p><i>Methods</i> - In this cross-sectional study, circulating levels of IL-18 and IL-18BP were analysed in ...

    • Serum Markers of Neuronal Damage and Astrocyte Activity in Patients with Chronic Epilepsy: Elevated Levels of Glial Fibrillary Acidic Protein 

      Mochol, Monika; Taubøll, Erik; Aukrust, Pål; Ueland, Thor; Andreassen, Ole; Svalheim, Sigrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-07)
      Objectives. Blood-brain barrier (BBB) dysfunction is one of the key pathogenic mechanisms in the development of epilepsy. There is therefore an increasing need to identify BBB biomarkers as these will have prognostic and therapeutic implications. The purpose of this study was to assess the levels of the BBB permeability markers, glial fibrillary acidic protein (GFAP), neuron-specific enolase ...